The Los Angeles County Medical Examiner’s Office toxicology test states that Matthew Perry perished from “the acute effects of ketamine.” It’s unclear how exactly the intake process is done. The “Friends” actor’s death was caused in part by cardiac artery disease, drowning, and the negative effects of buprenorphine, which is used for the treatment of opioid use disorder. It was determined that the death was a result of negligence.
Before his death, Perry had been receiving ketamine infusion therapy for depression and anxiety. The toxicology assessment goes on to say “At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression.” In the 1990s and early 2000s, Perry gained popularity as the witty and sarcastic Chandler Bing on the television series “Friends.” Over ten seasons, he starred in over 200 episodes of the NBC satire.
In an announcement released after learning of Perry’s passing, Jennifer Aniston, Courteney Cox, Lisa Kudrow, Matt LeBlanc, and David Schwimmer stated, “We are all so utterly devastated by the loss of Matthew. We were more than just cast mates. We are a family. There is so much to say, but right now we’re going to take a moment to grieve and process this unfathomable loss. In time we will say more, as and when we are able. For now, our thoughts and our love are with Matty’s family, his friends, and everyone who loved him around the world.”